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Magnification Prior: A Self-Supervised Method for Learning Representations on Breast Cancer Histopathological Images

15 Mar 2022arXiv:2203.07707archive 2025-07-28

Prakash Chandra Chhipa, Richa Upadhyay, Gustav Grund Pihlgren, Rajkumar Saini, Seiichi Uchida, Marcus Liwicki

This work presents a novel self-supervised pre-training method to learn efficient representations without labels on histopathology medical images utilizing magnification factors. Other state-of-theart works mainly focus on fully supervised learning approaches that rely heavily on human annotations. However, the scarcity of labeled and unlabeled data is a long-standing challenge in histopathology. Currently, representation learning without labels remains unexplored for the histopathology domain. The proposed method, Magnification Prior Contrastive Similarity (MPCS), enables self-supervised learning of representations without labels on small-scale breast cancer dataset BreakHis by exploiting magnification factor, inductive transfer, and reducing human prior. The proposed method matches fully supervised learning state-of-the-art performance in malignancy classification when only 20% of labels are used in fine-tuning and outperform previous works in fully supervised learning settings. It formulates a hypothesis and provides empirical evidence to support that reducing human-prior leads to efficient representation learning in self-supervision. The implementation of this work is available online on GitHub - https://github.com/prakashchhipa/Magnification-Prior-Self-Supervised-Method

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prakashchhipa/magnification-prior-self-supervised-method officialmentioned in papermentioned on GitHubpytorch report

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Tasks

Breast Cancer Histology Image ClassificationBreast Cancer Histology Image Classification (20% labels)Classification Of Breast Cancer Histology ImagesRepresentation LearningSelf-Supervised Learning

Results from the paper archive 2025-07-28

TaskDatasetModelMetricValueRank at snapshotLeaderboardReport
Breast Cancer Histology Image Classification BreakHis EfficientNet-b2 1:1 Accuracy 92.23 #5 of 5 Archive leaderboard report
Breast Cancer Histology Image Classification BreakHis EfficientNet-b2 Accuracy (Inter-Patient) 92.15 #5 of 5 Archive leaderboard report
Breast Cancer Histology Image Classification (20% labels) BreakHis EfficientNet-b2 1:1 Accuracy 88.77 #1 of 1 Archive leaderboard report
Breast Cancer Histology Image Classification (20% labels) BreakHis EfficientNet-b2 Accuracy (Inter-Patient) 88.77 #1 of 1 Archive leaderboard report

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Methods

Introduced by this paper: Magnification Prior Contrastive Similarity

Magnification Prior Contrastive Similarity

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