Papers › A New Graph Node Classification Benchmark: Learning Structure from Histology Cell Graphs

A New Graph Node Classification Benchmark: Learning Structure from Histology Cell Graphs

11 Nov 2022arXiv:2211.06292archive 2025-07-28

Claudia Vanea, Jonathan Campbell, Omri Dodi, Liis Salumäe, Karen Meir, Drorith Hochner-Celnikier, Hagit Hochner, Triin Laisk, Linda M. Ernst, Cecilia M. Lindgren, Christoffer Nellåker

We introduce a new benchmark dataset, Placenta, for node classification in an underexplored domain: predicting microanatomical tissue structures from cell graphs in placenta histology whole slide images. This problem is uniquely challenging for graph learning for a few reasons. Cell graphs are large (>1 million nodes per image), node features are varied (64-dimensions of 11 types of cells), class labels are imbalanced (9 classes ranging from 0.21% of the data to 40.0%), and cellular communities cluster into heterogeneously distributed tissues of widely varying sizes (from 11 nodes to 44,671 nodes for a single structure). Here, we release a dataset consisting of two cell graphs from two placenta histology images totalling 2,395,747 nodes, 799,745 of which have ground truth labels. We present inductive benchmark results for 7 scalable models and show how the unique qualities of cell graphs can help drive the development of novel graph neural network architectures.

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nellaker-group/placenta officialmentioned in papermentioned on GitHubpytorchMIT report

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get_nodes_within_tiles Nellaker-group/placenta/placenta/dataset.py official repository unverified MIT (permissive) · 3b76433c473cb3c9 · report
get_tissue_confusion_matrix Nellaker-group/placenta/placenta/evaluation_plots.py official repository unverified MIT (permissive) · 0cf316f93d5ce978 · report
setup_run Nellaker-group/placenta/placenta/utils.py official repository unverified MIT (permissive) · 126c3b301e4eb0d5 · report

Tasks

Graph LearningGraph Neural NetworkNode Classificationwhole slide images

Datasets

Introduced by this paper, per the archive.

Placenta

Results from the paper archive 2025-07-28

TaskDatasetModelMetricValueRank at snapshotLeaderboardReport
Node Classification Placenta GraphSAGE Accuracy (%) 64.88±0.43 #1 of 5 Archive leaderboard report
Node Classification Placenta SIGN Accuracy (%) 64.77±0.43 #2 of 5 Archive leaderboard report
Node Classification Placenta ClusterGCN Accuracy (%) 64.24±1.21 #3 of 5 Archive leaderboard report
Node Classification Placenta GraphSAINT Accuracy (%) 63.94±0.23 #4 of 5 Archive leaderboard report
Node Classification Placenta ShaDow Accuracy (%) 63.04±0.77 #5 of 5 Archive leaderboard report

Ranks are positions in the archive's leaderboards as they stood at the 2025-07-28 snapshot. Results published since then are not among these rows, so a rank here is not a current standing.

Methods

Cluster-GCNGATGATv2Graph Neural NetworkGraphSAGEGraphSAINT

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