Papers › A Comparative Study of Graph Neural Networks for Shape Classification in Neuroimaging

A Comparative Study of Graph Neural Networks for Shape Classification in Neuroimaging

29 Oct 2022arXiv:2210.16670archive 2025-07-28

Nairouz Shehata, Wulfie Bain, Ben Glocker

Graph neural networks have emerged as a promising approach for the analysis of non-Euclidean data such as meshes. In medical imaging, mesh-like data plays an important role for modelling anatomical structures, and shape classification can be used in computer aided diagnosis and disease detection. However, with a plethora of options, the best architectural choices for medical shape analysis using GNNs remain unclear. We conduct a comparative analysis to provide practitioners with an overview of the current state-of-the-art in geometric deep learning for shape classification in neuroimaging. Using biological sex classification as a proof-of-concept task, we find that using FPFH as node features substantially improves GNN performance and generalisation to out-of-distribution data; we compare the performance of three alternative convolutional layers; and we reinforce the importance of data augmentation for graph based learning. We then confirm these results hold for a clinically relevant task, using the classification of Alzheimer's disease.

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