Papers › ViT-2SPN: Vision Transformer-based Dual-Stream Self-Supervised Pretraining Networks...

ViT-2SPN: Vision Transformer-based Dual-Stream Self-Supervised Pretraining Networks for Retinal OCT Classification

28 Jan 2025arXiv:2501.17260archive 2025-07-28

Mohammadreza Saraei, Igor Kozak, Eung-Joo Lee

Optical Coherence Tomography (OCT) is a non-invasive imaging modality essential for diagnosing various eye diseases. Despite its clinical significance, developing OCT-based diagnostic tools faces challenges, such as limited public datasets, sparse annotations, and privacy concerns. Although deep learning has made progress in automating OCT analysis, these challenges remain unresolved. To address these limitations, we introduce the Vision Transformer-based Dual-Stream Self-Supervised Pretraining Network (ViT-2SPN), a novel framework designed to enhance feature extraction and improve diagnostic accuracy. ViT-2SPN employs a three-stage workflow: Supervised Pretraining, Self-Supervised Pretraining (SSP), and Supervised Fine-Tuning. The pretraining phase leverages the OCTMNIST dataset (97,477 unlabeled images across four disease classes) with data augmentation to create dual-augmented views. A Vision Transformer (ViT-Base) backbone extracts features, while a negative cosine similarity loss aligns feature representations. Pretraining is conducted over 50 epochs with a learning rate of 0.0001 and momentum of 0.999. Fine-tuning is performed on a stratified 5.129% subset of OCTMNIST using 10-fold cross-validation. ViT-2SPN achieves a mean AUC of 0.93, accuracy of 0.77, precision of 0.81, recall of 0.75, and an F1 score of 0.76, outperforming existing SSP-based methods.

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Tasks

Data Augmentation Diagnostic Medical Image Classification Retinal OCT Disease Classification Self-Supervised Learning

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Absolute Position Encodings Adam Attention BPE Dense Connections Dropout Label Smoothing Layer Normalization Linear Layer Multi-Head Attention Position-Wise Feed-Forward Layer Residual Connection Softmax Transformer Vision Transformer

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