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Ontology-driven weak supervision for clinical entity classification in electronic health records

5 Aug 2020arXiv:2008.01972archive 2025-07-28

Jason A. Fries, Ethan Steinberg, Saelig Khattar, Scott L. Fleming, Jose Posada, Alison Callahan, Nigam H. Shah

In the electronic health record, using clinical notes to identify entities such as disorders and their temporality (e.g. the order of an event relative to a time index) can inform many important analyses. However, creating training data for clinical entity tasks is time consuming and sharing labeled data is challenging due to privacy concerns. The information needs of the COVID-19 pandemic highlight the need for agile methods of training machine learning models for clinical notes. We present Trove, a framework for weakly supervised entity classification using medical ontologies and expert-generated rules. Our approach, unlike hand-labeled notes, is easy to share and modify, while offering performance comparable to learning from manually labeled training data. In this work, we validate our framework on six benchmark tasks and demonstrate Trove's ability to analyze the records of patients visiting the emergency department at Stanford Health Care for COVID-19 presenting symptoms and risk factors.

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bert_tokenizer som-shahlab/trove/applications/bc5cdr/chemicals.py official repository ran · our draft was wrong Apache-2.0 (permissive) · e52b3b8ca1b4fc81 · report
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Tasks

General ClassificationNamed Entity Recognition (NER)Temporal Information ExtractionWeakly Supervised ClassificationWeakly-Supervised Named Entity Recognition

Results from the paper archive 2025-07-28

TaskDatasetModelMetricValueRank at snapshotLeaderboardReport
Weakly Supervised Classification ShARe/CLEF 2014: Task 2 Disorders Trove F1 92.7 #1 of 1 Archive leaderboard report
Weakly Supervised Classification THYME-2016 Trove F1 72.9 #1 of 1 Archive leaderboard report

Ranks are positions in the archive's leaderboards as they stood at the 2025-07-28 snapshot. Results published since then are not among these rows, so a rank here is not a current standing.

Methods

AdamAttentionBERTDense ConnectionsDropoutLayer NormalizationLinear LayerLinear WarmupMulti-Head AttentionSoftmaxWordPiece

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