Papers › Trans2Unet: Neural fusion for Nuclei Semantic Segmentation

Trans2Unet: Neural fusion for Nuclei Semantic Segmentation

24 Jul 2024arXiv:2407.17181archive 2025-07-28

Dinh-Phu Tran, Quoc-Anh Nguyen, Van-Truong Pham, Thi-Thao Tran

Nuclei segmentation, despite its fundamental role in histopathological image analysis, is still a challenge work. The main challenge of this task is the existence of overlapping areas, which makes separating independent nuclei more complicated. In this paper, we propose a new two-branch architecture by combining the Unet and TransUnet networks for nuclei segmentation task. In the proposed architecture, namely Trans2Unet, the input image is first sent into the Unet branch whose the last convolution layer is removed. This branch makes the network combine features from different spatial regions of the input image and localizes more precisely the regions of interest. The input image is also fed into the second branch. In the second branch, which is called TransUnet branch, the input image will be divided into patches of images. With Vision transformer (ViT) in architecture, TransUnet can serve as a powerful encoder for medical image segmentation tasks and enhance image details by recovering localized spatial information. To boost up Trans2Unet efficiency and performance, we proposed to infuse TransUnet with a computational-efficient variation called "Waterfall" Atrous Spatial Pooling with Skip Connection (WASP-KC) module, which is inspired by the "Waterfall" Atrous Spatial Pooling (WASP) module. Experiment results on the 2018 Data Science Bowl benchmark show the effectiveness and performance of the proposed architecture while compared with previous segmentation models.

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Tasks

Image SegmentationMedical Image SegmentationSegmentationSemantic Segmentation

Results from the paper archive 2025-07-28

TaskDatasetModelMetricValueRank at snapshotLeaderboardReport
Medical Image Segmentation 2018 Data Science Bowl Trans2Unet Dice 0.9225 #5 of 10 Archive leaderboard report
Medical Image Segmentation 2018 Data Science Bowl Trans2Unet mIoU 0.8614 #5 of 10 Archive leaderboard report
Medical Image Segmentation GlaS Trans2Unet Dice 89.84 #4 of 10 Archive leaderboard report
Medical Image Segmentation GlaS Trans2Unet F1 89.84 #4 of 10 Archive leaderboard report
Medical Image Segmentation GlaS Trans2Unet IoU 82.54 #4 of 10 Archive leaderboard report

Ranks are positions in the archive's leaderboards as they stood at the 2025-07-28 snapshot. Results published since then are not among these rows, so a rank here is not a current standing.

Methods

AttentionConvolutionDense ConnectionsLayer NormalizationLinear LayerMulti-Head AttentionResidual ConnectionSoftmaxVision Transformer

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