Papers › pyscreener: A Python Wrapper for Computational Docking Software

pyscreener: A Python Wrapper for Computational Docking Software

17 Dec 2021arXiv:2112.10575archive 2025-07-28

David E. Graff, Connor W. Coley

pyscreener is a Python library that seeks to alleviate the challenges of large-scale structure-based design using computational docking. It provides a simple and uniform interface that is agnostic to the backend docking engine with which to calculate the docking score of a given molecule in a specified active site. Additionally, pyscreener features first-class support for task distribution, allowing users to seamlessly scale their code from a local, multi-core setup to a large, heterogeneous resource allocation.

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