Papers › Patient Contrastive Learning: a Performant, Expressive, and Practical Approach to ECG Modeling

Patient Contrastive Learning: a Performant, Expressive, and Practical Approach to ECG Modeling

9 Apr 2021arXiv:2104.04569archive 2025-07-28

Nathaniel Diamant, Erik Reinertsen, Steven Song, Aaron Aguirre, Collin Stultz, Puneet Batra

Supervised machine learning applications in health care are often limited due to a scarcity of labeled training data. To mitigate this effect of small sample size, we introduce a pre-training approach, Patient Contrastive Learning of Representations (PCLR), which creates latent representations of ECGs from a large number of unlabeled examples. The resulting representations are expressive, performant, and practical across a wide spectrum of clinical tasks. We develop PCLR using a large health care system with over 3.2 million 12-lead ECGs, and demonstrate substantial improvements across multiple new tasks when there are fewer than 5,000 labels. We release our model to extract ECG representations at https://github.com/broadinstitute/ml4h/tree/master/model_zoo/PCLR.

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Contrastive LearningElectrocardiography (ECG)Unsupervised Pre-training

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1x1 ConvolutionAverage PoolingBatch NormalizationBottleneck Residual BlockColorJitterContrastive LearningConvolutionDense ConnectionsFeedforward NetworkGlobal Average PoolingKaiming InitializationMax PoolingNT-XentRandom Gaussian BlurRandom Resized CropReLUResidual BlockResidual ConnectionSimCLR

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