Papers › Network structure of cascading neural systems predicts stimulus propagation and recovery

Network structure of cascading neural systems predicts stimulus propagation and recovery

10 Nov 2019arXiv:1812.09361archive 2025-07-28

Many neural systems display cascading behavior characterized by uninterrupted sequences of neuronal firing. This gap precludes an understanding of how variations in network structure manifest in neural dynamics and either support or impinge upon information processing. Here, we develop a theoretical understanding of how network structure supports information processing through network dynamics, and we validate our theory with empirical data. Using a generalized spiking model and mathematical tools from linear systems theory, network control theory, and information theory, we show how network structure can be designed to temporally extend the propagation and recovery of certain stimulus patterns. Moreover, we observe cycles as structural and dynamic motifs that are prevalent in such networks. Broadly, our results demonstrate how cascading neural networks could contribute to cognitive faculties that require lasting activation of neuronal patterns, such as working memory or attention.

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