Papers › M-FLAG: Medical Vision-Language Pre-training with Frozen Language Models and Latent...

M-FLAG: Medical Vision-Language Pre-training with Frozen Language Models and Latent Space Geometry Optimization

17 Jul 2023arXiv:2307.08347archive 2025-07-28

Che Liu, Sibo Cheng, Chen Chen, Mengyun Qiao, Weitong Zhang, Anand Shah, Wenjia Bai, Rossella Arcucci

Medical vision-language models enable co-learning and integrating features from medical imaging and clinical text. However, these models are not easy to train and the latent representation space can be complex. Here we propose a novel way for pre-training and regularising medical vision-language models. The proposed method, named Medical vision-language pre-training with Frozen language models and Latent spAce Geometry optimization (M-FLAG), leverages a frozen language model for training stability and efficiency and introduces a novel orthogonality loss to harmonize the latent space geometry. We demonstrate the potential of the pre-trained model on three downstream tasks: medical image classification, segmentation, and object detection. Extensive experiments across five public datasets demonstrate that M-FLAG significantly outperforms existing medical vision-language pre-training approaches and reduces the number of parameters by 78\%. Notably, M-FLAG achieves outstanding performance on the segmentation task while using only 1\% of the RSNA dataset, even outperforming ImageNet pre-trained models that have been fine-tuned using 100\% of the data.

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Image ClassificationLanguage ModelingLanguage ModellingMedical Image ClassificationObject Detectionimage-classificationobject-detection

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