Papers › Less-supervised learning with knowledge distillation for sperm morphology analysis

Less-supervised learning with knowledge distillation for sperm morphology analysis

8 May 2024Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization 2024 5archive 2025-07-28

Ali Nabipour, Mohammad Javad Shams Nejati, Yasaman Boreshban, Seyed Abolghasem Mirroshandel

Sperm Morphology Analysis (SMA) is pivotal in diagnosing male infertility. However, manual analysis is subjective and time-intensive. Artificial intelligence presents automated alternatives, but hurdles like limited data and image quality constraints hinder its efficacy. These challenges impede Deep Learning (DL) models from grasping crucial sperm features. A solution enabling DL models to learn sample nuances, even with limited data, would be invaluable. This study proposes a Knowledge Distillation (KD) method to distinguish normal from abnormal sperm cells, leveraging the Modified Human Sperm Morphology Analysis dataset. Despite low-resolution, blurry images, our method yields relevant results. We exclusively utilize normal samples to train the model for anomaly detection, crucial in scenarios lacking abnormal data – a common issue in medical tasks. Our aim is to train an Anomaly Detection model using a dataset comprising unclear images and limited samples, without direct exposure to abnormal data. Our method achieves Receiver ROC/AUC scores of 70.4%, 87.6%, and 71.1% for head, vacuole, and acrosome, respectively, our method matches traditional DL model performance with less than 70% of the data. This less-supervised approach shows promise in advancing SMA despite data scarcity. Furthermore, KD enables model adaptability to edge devices in fertility clinics, requiring less processing power.

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Anomaly DetectionKnowledge DistillationUnsupervised Anomaly Detection

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Knowledge DistillationSMA

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