Papers › Bayesian calibration of bubble size dynamics applied to CO2 gas fermenters

Bayesian calibration of bubble size dynamics applied to CO2 gas fermenters

30 Apr 2024arXiv:2404.19636links table onlyarchive 2025-07-28

Malik Hassanaly, John M. Parra-Alvarez, Mohammad J. Rahimi, Federico Municchi, Hariswaran Sitaraman

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To accelerate the scale-up of gaseous CO2 fermentation reactors, computational models need to predict gas-to-liquid mass transfer which requires capturing the bubble size dynamics, i.e. bubble breakup and coalescence. However, the applicability of existing models beyond air-water mixtures remains to be established. Here, an inverse modeling approach, accelerated with a neural network surrogate, calibrates the breakup and coalescence closure models, that are used in class methods for population balance modeling (PBM). The calibration is performed based on experimental results obtained in a CO2-air-water-coflowing bubble column reactor. Bayesian inference is used to account for noise in the experimental dataset and bias in the simulation results. To accurately capture gas holdup and interphase mass transfer, the results show that the breakage rate needs to be increased by one order of magnitude. The inferred model parameters are then used on a separate configuration and shown to also improve bubble size distribution predictions.

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