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HoVer-UNet: Accelerating HoVerNet with UNet-based multi-class nuclei segmentation via knowledge distillation

21 Nov 2023arXiv:2311.12553archive 2025-07-28

Cristian Tommasino, Cristiano Russo, Antonio Maria Rinaldi, Francesco Ciompi

We present HoVer-UNet, an approach to distill the knowledge of the multi-branch HoVerNet framework for nuclei instance segmentation and classification in histopathology. We propose a compact, streamlined single UNet network with a Mix Vision Transformer backbone, and equip it with a custom loss function to optimally encode the distilled knowledge of HoVerNet, reducing computational requirements without compromising performances. We show that our model achieved results comparable to HoVerNet on the public PanNuke and Consep datasets with a three-fold reduction in inference time. We make the code of our model publicly available at https://github.com/DIAGNijmegen/HoVer-UNet.

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Instance SegmentationKnowledge DistillationSemantic Segmentation

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Absolute Position EncodingsAdamAttentionBPEDense ConnectionsDropoutLabel SmoothingLayer NormalizationLinear LayerMulti-Head AttentionPosition-Wise Feed-Forward LayerResidual ConnectionSoftmaxTransformerVision Transformer

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