Papers › Bayesian Graph Neural Networks for Molecular Property Prediction

Bayesian Graph Neural Networks for Molecular Property Prediction

25 Nov 2020arXiv:2012.02089archive 2025-07-28

George Lamb, Brooks Paige

Graph neural networks for molecular property prediction are frequently underspecified by data and fail to generalise to new scaffolds at test time. A potential solution is Bayesian learning, which can capture our uncertainty in the model parameters. This study benchmarks a set of Bayesian methods applied to a directed MPNN, using the QM9 regression dataset. We find that capturing uncertainty in both readout and message passing parameters yields enhanced predictive accuracy, calibration, and performance on a downstream molecular search task.

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Molecular Property PredictionPredictionProperty Predictionregression

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MPNN

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