Papers › 3D U²-Net: A 3D Universal U-Net for Multi-Domain Medical Image Segmentation
3D U²-Net: A 3D Universal U-Net for Multi-Domain Medical Image Segmentation
Chao Huang, Hu Han, Qingsong Yao, Shankuan Zhu, S. Kevin Zhou
Fully convolutional neural networks like U-Net have been the state-of-the-art methods in medical image segmentation. Practically, a network is highly specialized and trained separately for each segmentation task. Instead of a collection of multiple models, it is highly desirable to learn a universal data representation for different tasks, ideally a single model with the addition of a minimal number of parameters steered to each task. Inspired by the recent success of multi-domain learning in image classification, for the first time we explore a promising universal architecture that handles multiple medical segmentation tasks and is extendable for new tasks, regardless of different organs and imaging modalities. Our 3D Universal U-Net (3D U²-Net) is built upon separable convolution, assuming that {\it images from different domains have domain-specific spatial correlations which can be probed with channel-wise convolution while also share cross-channel correlations which can be modeled with pointwise convolution}. We evaluate the 3D U²-Net on five organ segmentation datasets. Experimental results show that this universal network is capable of competing with traditional models in terms of segmentation accuracy, while requiring only about 1% of the parameters. Additionally, we observe that the architecture can be easily and effectively adapted to a new domain without sacrificing performance in the domains used to learn the shared parameterization of the universal network. We put the code of 3D U²-Net into public domain. \url{https://github.com/huangmozhilv/u2net_torch/}
Code
Repository list and official/mentioned flags are the archive's, frozen 2025-07-28. Reachability, where shown, is from one Syntology probe window (2026-09-16 to 2026-09-18); repositories not probed show nothing. GitHub stars are not tracked.
Code Syntology ran Syntology
Not run by Syntology. Nothing on this page verifies that the listed code works.
Tasks
Results from the paper archive 2025-07-28
No leaderboard rows for this paper in the archive.
Methods
Report a problem or propose a change · a person checks every report against the paper or source before anything changes; decisions are listed on /corrections