Datasets › Decagon

Decagon (Bio-decagon)

Introduced by Marinka Zitnik et al. in Modeling polypharmacy side effects with graph convolutional networks2 Feb 2018 archive 2025-07-28

Bio-decagon is a dataset for polypharmacy side effect identification problem framed as a multirelational link prediction problem in a two-layer multimodal graph/network of two node types: drugs and proteins. Protein-protein interaction network describes relationships between proteins. Drug-drug interaction network contains 964 different types of edges (one for each side effect type) and describes which drug pairs lead to which side effects. Lastly, drug-protein links describe the proteins targeted by a given drug.

The final network after linking entity vocabularies used by different databases has 645 drug and 19,085 protein nodes connected by 715,612 protein-protein, 4,651,131 drug-drug, and 18,596 drug-protein edges.

Source: Modeling polypharmacy side effects with graph convolutional networks Image Source: Modeling polypharmacy side effects with graph convolutional networks

Benchmarks archive 2025-07-28

All 1 leaderboard whose dataset resolves to this page shown (sort by any header). "First row" is the archive's own first row at snapshot, in the archive's row order; nothing here re-ranks and metric direction is not asserted.

First row (archive order)PaperCode
Link Prediction Decagon Decagon AUROC 0.872 Modeling polypharmacy side effects with graph... mims-harvard/decagon 2 Compare

Papers archive 2025-07-28

2 shown of 2 papers with a leaderboard row on this dataset's benchmarks, newest first. The archive's own "papers using this dataset" list was never published, so this is the benchmark-backed subset; the archive's count for this dataset is 33. The Syntology column is from Syntology's graph (read 2026-09-24), stated per sample; it is not part of any archive number.

DateSamples run Syntology
Tri-graph Information Propagation for Polypharmacy Side Effect Prediction 1 1 28 Jan 2020 not harvested
Modeling polypharmacy side effects with graph convolutional networks 1 1 2 Feb 2018 not harvested

Dataset loaders archive 2025-07-28

No loader listed in the archive.

Tasks archive 2025-07-28

License archive 2025-07-28

Unknown

Modalities archive 2025-07-28

Languages archive 2025-07-28

No language tagged.

Variants archive 2025-07-28

  • Decagon

1 variant name, as the archive lists them.

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