{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/self-supervised-oct-image-denoising-with","title":"Self-supervised OCT Image Denoising with Slice-to-Slice Registration and Reconstruction","arxiv_id":"2311.15167","date":"2023-11-26","proceeding":null,"authors":["Shijie Li","Palaiologos Alexopoulos","Anse Vellappally","Ronald Zambrano","Wollstein Gadi","Guido Gerig"],"abstract":"Strong speckle noise is inherent to optical coherence tomography (OCT) imaging and represents a significant obstacle for accurate quantitative analysis of retinal structures which is key for advances in clinical diagnosis and monitoring of disease. Learning-based self-supervised methods for structure-preserving noise reduction have demonstrated superior performance over traditional methods but face unique challenges in OCT imaging. The high correlation of voxels generated by coherent A-scan beams undermines the efficacy of self-supervised learning methods as it violates the assumption of independent pixel noise. We conduct experiments demonstrating limitations of existing models due to this independence assumption. We then introduce a new end-to-end self-supervised learning framework specifically tailored for OCT image denoising, integrating slice-by-slice training and registration modules into one network. An extensive ablation study is conducted for the proposed approach. Comparison to previously published self-supervised denoising models demonstrates improved performance of the proposed framework, potentially serving as a preprocessing step towards superior segmentation performance and quantitative analysis.","url_abs":"https://arxiv.org/abs/2311.15167v2","url_pdf":"https://arxiv.org/pdf/2311.15167v2.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"self-supervised-oct-image-denoising-with","repo_url":"https://github.com/cjlee94/slice2slice","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":0,"framework":"pytorch","reach":null}],"tasks":[{"task_slug":"denoising","task_name":"Denoising"},{"task_slug":"image-denoising","task_name":"Image Denoising"},{"task_slug":"self-supervised-learning","task_name":"Self-Supervised Learning"}],"methods":[],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}