{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/quantitative-photoacoustic-oximetry-imaging","title":"Quantitative photoacoustic oximetry imaging by multiple illumination learned spectral decoloring","arxiv_id":"2102.11201","date":"2021-02-22","proceeding":null,"authors":["Thomas Kirchner","Martin Frenz"],"abstract":"Significance: Quantitative measurement of blood oxygen saturation (sO$_2$) with photoacoustic (PA) imaging is one of the most sought after goals of quantitative PA imaging research due to its wide range of biomedical applications. Aim: A method for accurate and applicable real-time quantification of local sO$_2$ with PA imaging. Approach: We combine multiple illumination (MI) sensing with learned spectral decoloring (LSD); training on Monte Carlo simulations of spectrally colored absorbed energy spectra, in order to apply the trained models to real PA measurements. We validate our combined MI-LSD method on a highly reliable, reproducible and easily scalable phantom model, based on copper and nickel sulfate solutions. Results: With this sulfate model we see a consistently high estimation accuracy using MI-LSD, with median absolute estimation errors of 2.5 to 4.5 percentage points. We further find fewer outliers in MI-LSD estimates compared to LSD. Random forest regressors outperform previously reported neural network approaches. Conclusions: Random forest based MI-LSD is a promising method for accurate quantitative PA oximetry imaging.","url_abs":"https://arxiv.org/abs/2102.11201v1","url_pdf":"https://arxiv.org/pdf/2102.11201v1.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"quantitative-photoacoustic-oximetry-imaging","repo_url":"https://github.com/thkirchner/PA-MI-LSD","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":0,"framework":"pytorch","reach":null},{"paper_slug":"quantitative-photoacoustic-oximetry-imaging","repo_url":"https://github.com/FMatti/ALE-LSD","is_official":0,"mentioned_in_paper":0,"mentioned_in_github":1,"framework":"none","reach":{"status":"ok","spdx":"BSD-3-Clause"}}],"tasks":[],"methods":[],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}