{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/privacy-preserving-collaborative-machine","title":"Privacy-preserving collaborative machine learning on genomic data using TensorFlow","arxiv_id":"2002.04344","date":"2020-02-11","proceeding":null,"authors":["Cheng Hong","Zhicong Huang","Wen-jie Lu","Hunter Qu","Li Ma","Morten Dahl","Jason Mancuso"],"abstract":"Machine learning (ML) methods have been widely used in genomic studies. However, genomic data are often held by different stakeholders (e.g. hospitals, universities, and healthcare companies) who consider the data as sensitive information, even though they desire to collaborate. To address this issue, recent works have proposed solutions using Secure Multi-party Computation (MPC), which train on the decentralized data in a way that the participants could learn nothing from each other beyond the final trained model. We design and implement several MPC-friendly ML primitives, including class weight adjustment and parallelizable approximation of activation function. In addition, we develop the solution as an extension to TF Encrypted~\\citep{dahl2018private}, enabling us to quickly experiment with enhancements of both machine learning techniques and cryptographic protocols while leveraging the advantages of TensorFlow's optimizations. Our implementation compares favorably with state-of-the-art methods, winning first place in Track IV of the iDASH2019 secure genome analysis competition.","url_abs":"https://arxiv.org/abs/2002.04344v1","url_pdf":"https://arxiv.org/pdf/2002.04344v1.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"links_only","authors_date_abstract":"arXiv metadata, CC0 1.0 (https://info.arxiv.org/help/license), from the Kaggle arXiv metadata snapshot of 2026-09-12"},"code_links":[{"paper_slug":"privacy-preserving-collaborative-machine","repo_url":"https://github.com/tf-encrypted/tf-encrypted","is_official":0,"mentioned_in_paper":0,"mentioned_in_github":1,"framework":"tf","reach":null}],"tasks":[],"methods":[],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"atlas_url":"https://app.syntology.ai/?focus=2002.04344","mcp":{"get_harvested_code_for_paper":{"arxiv_id":"2002.04344"}},"developers":"https://syntology.ai/developers","read_at":"2026-09-24T18:15:14+00:00","read_at_is":"when the build read Syntology's graph, not when any sample ran","claim":"Per-sample execution status on synthesized fixtures; not a correctness claim about the paper. Samples come from repositories linked to the paper, official or community; repo_kind says which.","repos":[{"provenance":"external:paperswithcode_snapshot_2025-07-28","url":"https://github.com/tf-encrypted/tf-encrypted","reach":null}],"summary":{"ran_violates":1,"ran_honours":2},"by_repo_kind":{},"repo_kind_vocabulary":{"official":"The archive marks this repository official for the paper","named_in_paper":"The archive records that the paper mentions this repository; it is not marked official","listed":"In the archive's code links for this paper, not marked official and not recorded as mentioned in the paper","found_in_text":"Syntology found this repository in the paper's own text; whether it is the authors' implementation is not asserted","community":"Not in the archive's code links for this paper; a community repository Syntology harvested"},"n_pointer_only_for_licence":3,"samples":[{"code_sha256_prefix":"75eee8867ebaae8d","entry":"is_power_of_two","repo":null,"repo_kind":null,"path":null,"file_url":null,"link_basis":"identical_code_first_harvested_elsewhere","language":"python","status":"ran_violates","verification_level":1,"contract_check":"VIOLATES","metamorphic_tier":"deterministic","behaviour_fingerprint":true,"licence":null,"inline_ok":false,"mcp_get_code":{"code_sha256":"75eee8867ebaae8d"}},{"code_sha256_prefix":"66cf0e56b4063f00","entry":"next_power_of_two","repo":null,"repo_kind":null,"path":null,"file_url":null,"link_basis":"identical_code_first_harvested_elsewhere","language":"python","status":"ran_honours","verification_level":1,"contract_check":"HONOURS","metamorphic_tier":"well_formed","behaviour_fingerprint":true,"licence":null,"inline_ok":false,"mcp_get_code":{"code_sha256":"66cf0e56b4063f00"}},{"code_sha256_prefix":"0e311f1934616d9e","entry":"prev_power_of_two_less_than","repo":null,"repo_kind":null,"path":null,"file_url":null,"link_basis":"identical_code_first_harvested_elsewhere","language":"python","status":"ran_honours","verification_level":1,"contract_check":"HONOURS","metamorphic_tier":"well_formed","behaviour_fingerprint":true,"licence":null,"inline_ok":false,"mcp_get_code":{"code_sha256":"0e311f1934616d9e"}}]},"arxiv_metadata":null,"syntology_extracted_results":null}