{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/pipvit-patch-based-visual-interpretable","title":"PiPViT: Patch-based Visual Interpretable Prototypes for Retinal Image Analysis","arxiv_id":"2506.10669","date":"2025-06-12","proceeding":null,"authors":["Marzieh Oghbaie","Teresa Araújoa","Hrvoje Bogunović"],"abstract":"Background and Objective: Prototype-based methods improve interpretability by learning fine-grained part-prototypes; however, their visualization in the input pixel space is not always consistent with human-understandable biomarkers. In addition, well-known prototype-based approaches typically learn extremely granular prototypes that are less interpretable in medical imaging, where both the presence and extent of biomarkers and lesions are critical. Methods: To address these challenges, we propose PiPViT (Patch-based Visual Interpretable Prototypes), an inherently interpretable prototypical model for image recognition. Leveraging a vision transformer (ViT), PiPViT captures long-range dependencies among patches to learn robust, human-interpretable prototypes that approximate lesion extent only using image-level labels. Additionally, PiPViT benefits from contrastive learning and multi-resolution input processing, which enables effective localization of biomarkers across scales. Results: We evaluated PiPViT on retinal OCT image classification across four datasets, where it achieved competitive quantitative performance compared to state-of-the-art methods while delivering more meaningful explanations. Moreover, quantitative evaluation on a hold-out test set confirms that the learned prototypes are semantically and clinically relevant. We believe PiPViT can transparently explain its decisions and assist clinicians in understanding diagnostic outcomes. Github page: https://github.com/marziehoghbaie/PiPViT","url_abs":"https://arxiv.org/abs/2506.10669v1","url_pdf":"https://arxiv.org/pdf/2506.10669v1.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"pipvit-patch-based-visual-interpretable","repo_url":"https://github.com/marziehoghbaie/pipvit","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":1,"framework":"pytorch","reach":null}],"tasks":[{"task_slug":"contrastive-learning","task_name":"Contrastive Learning"},{"task_slug":"diagnostic","task_name":"Diagnostic"},{"task_slug":"image-classification","task_name":"Image Classification"},{"task_slug":"image-classification","task_name":"image-classification"}],"methods":[{"method_slug":"attention","method_name":"Attention"},{"method_slug":"contrastive-learning","method_name":"Contrastive Learning"},{"method_slug":"dense-connections","method_name":"Dense Connections"},{"method_slug":"layer-normalization","method_name":"Layer Normalization"},{"method_slug":"linear-layer","method_name":"Linear Layer"},{"method_slug":"multi-head-attention","method_name":"Multi-Head Attention"},{"method_slug":"set","method_name":"SET"},{"method_slug":"softmax","method_name":"Softmax"},{"method_slug":"vision-transformer","method_name":"Vision Transformer"}],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}