{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/from-denoising-training-to-test-time","title":"From Denoising Training to Test-Time Adaptation: Enhancing Domain Generalization for Medical Image Segmentation","arxiv_id":"2310.20271","date":"2023-10-31","proceeding":null,"authors":["Ruxue Wen","Hangjie Yuan","Dong Ni","Wenbo Xiao","Yaoyao Wu"],"abstract":"In medical image segmentation, domain generalization poses a significant challenge due to domain shifts caused by variations in data acquisition devices and other factors. These shifts are particularly pronounced in the most common scenario, which involves only single-source domain data due to privacy concerns. To address this, we draw inspiration from the self-supervised learning paradigm that effectively discourages overfitting to the source domain. We propose the Denoising Y-Net (DeY-Net), a novel approach incorporating an auxiliary denoising decoder into the basic U-Net architecture. The auxiliary decoder aims to perform denoising training, augmenting the domain-invariant representation that facilitates domain generalization. Furthermore, this paradigm provides the potential to utilize unlabeled data. Building upon denoising training, we propose Denoising Test Time Adaptation (DeTTA) that further: (i) adapts the model to the target domain in a sample-wise manner, and (ii) adapts to the noise-corrupted input. Extensive experiments conducted on widely-adopted liver segmentation benchmarks demonstrate significant domain generalization improvements over our baseline and state-of-the-art results compared to other methods. Code is available at https://github.com/WenRuxue/DeTTA.","url_abs":"https://arxiv.org/abs/2310.20271v2","url_pdf":"https://arxiv.org/pdf/2310.20271v2.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"from-denoising-training-to-test-time","repo_url":"https://github.com/wenruxue/detta","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":1,"framework":"pytorch","reach":null}],"tasks":[{"task_slug":"decoder","task_name":"Decoder"},{"task_slug":"denoising","task_name":"Denoising"},{"task_slug":"domain-generalization","task_name":"Domain Generalization"},{"task_slug":"image-segmentation","task_name":"Image Segmentation"},{"task_slug":"liver-segmentation","task_name":"Liver Segmentation"},{"task_slug":"medical-image-segmentation","task_name":"Medical Image Segmentation"},{"task_slug":"self-supervised-learning","task_name":"Self-Supervised Learning"},{"task_slug":"semantic-segmentation","task_name":"Semantic Segmentation"},{"task_slug":"test-time-adaptation","task_name":"Test-time Adaptation"}],"methods":[{"method_slug":"concatenated-skip-connection","method_name":"Concatenated Skip Connection"},{"method_slug":"convolution","method_name":"Convolution"},{"method_slug":"max-pooling","method_name":"Max Pooling"},{"method_slug":"relu","method_name":"ReLU"},{"method_slug":"u-net","method_name":"U-Net"}],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"atlas_url":"https://app.syntology.ai/?focus=2310.20271","mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}