{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/delving-into-out-of-distribution-detection-1","title":"Delving into Out-of-Distribution Detection with Medical Vision-Language Models","arxiv_id":"2503.01020","date":"2025-03-02","proceeding":null,"authors":["Lie Ju","Sijin Zhou","Yukun Zhou","Huimin Lu","Zhuoting Zhu","Pearse A. Keane","ZongYuan Ge"],"abstract":"Recent advances in medical vision-language models (VLMs) demonstrate impressive performance in image classification tasks, driven by their strong zero-shot generalization capabilities. However, given the high variability and complexity inherent in medical imaging data, the ability of these models to detect out-of-distribution (OOD) data in this domain remains underexplored. In this work, we conduct the first systematic investigation into the OOD detection potential of medical VLMs. We evaluate state-of-the-art VLM-based OOD detection methods across a diverse set of medical VLMs, including both general and domain-specific purposes. To accurately reflect real-world challenges, we introduce a cross-modality evaluation pipeline for benchmarking full-spectrum OOD detection, rigorously assessing model robustness against both semantic shifts and covariate shifts. Furthermore, we propose a novel hierarchical prompt-based method that significantly enhances OOD detection performance. Extensive experiments are conducted to validate the effectiveness of our approach. The codes are available at https://github.com/PyJulie/Medical-VLMs-OOD-Detection.","url_abs":"https://arxiv.org/abs/2503.01020v1","url_pdf":"https://arxiv.org/pdf/2503.01020v1.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"delving-into-out-of-distribution-detection-1","repo_url":"https://github.com/pyjulie/medical-vlms-ood-detection","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":0,"framework":"pytorch","reach":null}],"tasks":[{"task_slug":"benchmarking","task_name":"Benchmarking"},{"task_slug":"image-classification","task_name":"Image Classification"},{"task_slug":"out-of-distribution-detection","task_name":"Out-of-Distribution Detection"},{"task_slug":"zero-shot-generalization","task_name":"Zero-shot Generalization"},{"task_slug":"image-classification","task_name":"image-classification"}],"methods":[{"method_slug":"set","method_name":"SET"}],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"syntology_url":null,"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}