{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/data-driven-tight-frame-for-cryo-em-image","title":"Data-Driven Tight Frame for Cryo-EM Image Denoising and Conformational Classification","arxiv_id":"1810.08829","date":"2018-10-20","proceeding":null,"authors":["Yin Xian","Hanlin Gu","Wei Wang","Xuhui Huang","Yuan Yao","Yang Wang","Jian-Feng Cai"],"abstract":"The cryo-electron microscope (cryo-EM) is increasingly popular these years. It helps to uncover the biological structures and functions of macromolecules. In this paper, we address image denoising problem in cryo-EM. Denoising the cryo-EM images can help to distinguish different molecular conformations and improve three dimensional reconstruction resolution. We introduce the use of data-driven tight frame (DDTF) algorithm for cryo-EM image denoising. The DDTF algorithm is closely related to the dictionary learning. The advantage of DDTF algorithm is that it is computationally efficient, and can well identify the texture and shape of images without using large data samples. Experimental results on cryo-EM image denoising and conformational classification demonstrate the power of DDTF algorithm for cryo-EM image denoising and classification.","url_abs":"http://arxiv.org/abs/1810.08829v2","url_pdf":"http://arxiv.org/pdf/1810.08829v2.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"links_only","authors_date_abstract":"arXiv metadata, CC0 1.0 (https://info.arxiv.org/help/license), from the Kaggle arXiv metadata snapshot of 2026-09-12"},"code_links":[{"paper_slug":"data-driven-tight-frame-for-cryo-em-image","repo_url":"https://github.com/poline3939/Cryo-EM-Denoising","is_official":0,"mentioned_in_paper":0,"mentioned_in_github":1,"framework":"none","reach":null}],"tasks":[],"methods":[],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}