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In contrast, we propose to solve instance segmentation from a new perspective. Instead of using instance-wise ROIs as inputs to a network of fixed weights, we employ dynamic instance-aware networks, conditioned on instances. CondInst enjoys two advantages: 1) Instance segmentation is solved by a fully convolutional network, eliminating the need for ROI cropping and feature alignment. 2) Due to the much improved capacity of dynamically-generated conditional convolutions, the mask head can be very compact (e.g., 3 conv. layers, each having only 8 channels), leading to significantly faster inference. We demonstrate a simpler instance segmentation method that can achieve improved performance in both accuracy and inference speed. On the COCO dataset, we outperform a few recent methods including well-tuned Mask RCNN baselines, without longer training schedules needed. 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