{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/compressive-image-scanning-microscope","title":"Compressive Image Scanning Microscope","arxiv_id":"2307.09841","date":"2023-07-19","proceeding":null,"authors":["Ajay Gunalan","Marco Castello","Simonluca Piazza","Shunlei Li","Alberto Diaspro","Leonardo S. Mattos","Paolo Bianchini"],"abstract":"We present a novel approach to implement compressive sensing in laser scanning microscopes (LSM), specifically in image scanning microscopy (ISM), using a single-photon avalanche diode (SPAD) array detector. Our method addresses two significant limitations in applying compressive sensing to LSM: the time to compute the sampling matrix and the quality of reconstructed images. We employ a fixed sampling strategy, skipping alternate rows and columns during data acquisition, which reduces the number of points scanned by a factor of four and eliminates the need to compute different sampling matrices. By exploiting the parallel images generated by the SPAD array, we improve the quality of the reconstructed compressive-ISM images compared to standard compressive confocal LSM images. Our results demonstrate the effectiveness of our approach in producing higher-quality images with reduced data acquisition time and potential benefits in reducing photobleaching.","url_abs":"https://arxiv.org/abs/2307.09841v1","url_pdf":"https://arxiv.org/pdf/2307.09841v1.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"compressive-image-scanning-microscope","repo_url":"https://github.com/ajaygunalan/BrightEyes-ISM/blob/main/compressive_ism/Compressive-ISM.ipynb","is_official":1,"mentioned_in_paper":0,"mentioned_in_github":0,"framework":"none","reach":null}],"tasks":[{"task_slug":"compressive-sensing","task_name":"Compressive Sensing"}],"methods":[],"datasets_introduced":[{"slug":"ism-images","name":"ISM Images","full_name":""}],"methods_introduced":[],"results":[],"syntology":{"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}