{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/communication-efficient-integrative","title":"Meta-analysis of heterogeneous data: integrative sparse regression in high-dimensions","arxiv_id":"1912.11928","date":"2019-12-26","proceeding":null,"authors":["Subha Maity","Yuekai Sun","Moulinath Banerjee"],"abstract":"We consider the task of meta-analysis in high-dimensional settings in which the data sources are similar but non-identical. To borrow strength across such heterogeneous datasets, we introduce a global parameter that emphasizes interpretability and statistical efficiency in the presence of heterogeneity. We also propose a one-shot estimator of the global parameter that preserves the anonymity of the data sources and converges at a rate that depends on the size of the combined dataset. For high-dimensional linear model settings, we demonstrate the superiority of our identification restrictions in adapting to a previously seen data distribution as well as predicting for a new/unseen data distribution. Finally, we demonstrate the benefits of our approach on a large-scale drug treatment dataset involving several different cancer cell-lines.","url_abs":"https://arxiv.org/abs/1912.11928v2","url_pdf":"https://arxiv.org/pdf/1912.11928v2.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"communication-efficient-integrative","repo_url":"https://github.com/smaityumich/mrlasso","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":0,"framework":"none","reach":null}],"tasks":[{"task_slug":"high","task_name":"Vocal Bursts Intensity Prediction"},{"task_slug":"regression-1","task_name":"regression"}],"methods":[],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}