{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/cervical-optical-coherence-tomography-image","title":"Cervical Optical Coherence Tomography Image Classification Based on Contrastive Self-Supervised Texture Learning","arxiv_id":"2108.05081","date":"2021-08-11","proceeding":null,"authors":["Kaiyi Chen","Qingbin Wang","Yutao Ma"],"abstract":"Background: Cervical cancer seriously affects the health of the female reproductive system. Optical coherence tomography (OCT) emerged as a non-invasive, high-resolution imaging technology for cervical disease detection. However, OCT image annotation is knowledge-intensive and time-consuming, which impedes the training process of deep-learning-based classification models. Purpose: This study aims to develop a computer-aided diagnosis (CADx) approach to classifying in-vivo cervical OCT images based on self-supervised learning. Methods: In addition to high-level semantic features extracted by a convolutional neural network (CNN), the proposed CADx approach leverages unlabeled cervical OCT images' texture features learned by contrastive texture learning. We conducted ten-fold cross-validation on the OCT image dataset from a multi-center clinical study on 733 patients from China. Results: In a binary classification task for detecting high-risk diseases, including high-grade squamous intraepithelial lesion and cervical cancer, our method achieved an area-under-the-curve value of 0.9798 plus or minus 0.0157 with a sensitivity of 91.17 plus or minus 4.99% and a specificity of 93.96 plus or minus 4.72% for OCT image patches; also, it outperformed two out of four medical experts on the test set. Furthermore, our method achieved a 91.53% sensitivity and 97.37% specificity on an external validation dataset containing 287 3D OCT volumes from 118 Chinese patients in a new hospital using a cross-shaped threshold voting strategy. Conclusions: The proposed contrastive-learning-based CADx method outperformed the end-to-end CNN models and provided better interpretability based on texture features, which holds great potential to be used in the clinical protocol of \"see-and-treat.\"","url_abs":"https://arxiv.org/abs/2108.05081v3","url_pdf":"https://arxiv.org/pdf/2108.05081v3.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"cervical-optical-coherence-tomography-image","repo_url":"https://github.com/whuchris/MIA-CTL","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":1,"framework":"pytorch","reach":null}],"tasks":[{"task_slug":"binary-classification","task_name":"Binary Classification"},{"task_slug":"contrastive-learning","task_name":"Contrastive Learning"},{"task_slug":"image-classification","task_name":"Image Classification"},{"task_slug":"self-supervised-learning","task_name":"Self-Supervised Learning"},{"task_slug":"sensitivity","task_name":"Sensitivity"},{"task_slug":"specificity","task_name":"Specificity"},{"task_slug":"image-classification","task_name":"image-classification"}],"methods":[],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"syntology_url":null,"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}