{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/caulking-the-leakage-effect-in-meeg-source","title":"Caulking the Leakage Effect in MEEG Source Connectivity Analysis","arxiv_id":"1810.00786","date":"2018-09-28","proceeding":null,"authors":["Deirel Paz-Linares","Eduardo Gonzalez-Moreira","Eduardo Martinez-Montes","Pedro A. Valdes-Hernandez","Jorge Bosch-Bayard","Maria Luisa Bringas-Vega","Pedro A. Valdes-Sosa"],"abstract":"Simplistic estimation of neural connectivity in MEEG sensor space is\nimpossible due to volume conduction. The only viable alternative is to carry\nout connectivity estimation in source space. Among the neuroscience community\nthis is claimed to be impossible or misleading due to Leakage: linear mixing of\nthe reconstructed sources. To address this problematic we propose a novel\nsolution method that caulks the Leakage in MEEG source activity and\nconnectivity estimates: BC-VARETA. It is based on a joint estimation of source\nactivity and connectivity in the frequency domain representation of MEEG time\nseries. To achieve this, we go beyond current methods that assume a fixed\ngaussian graphical model for source connectivity. In contrast we estimate this\ngraphical model in a Bayesian framework by placing priors on it, which allows\nfor highly optimized computations of the connectivity, via a new procedure\nbased on the local quadratic approximation under quite general prior models. A\nfurther contribution of this paper is the rigorous definition of leakage via\nthe Spatial Dispersion Measure and Earth Movers Distance based on the geodesic\ndistances over the cortical manifold. Both measures are extended for the first\ntime to quantify Connectivity Leakage by defining them on the cartesian product\nof cortical manifolds. Using these measures, we show that BC-VARETA outperforms\nmost state of the art inverse solvers by several orders of magnitude.","url_abs":"http://arxiv.org/abs/1810.00786v1","url_pdf":"http://arxiv.org/pdf/1810.00786v1.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"caulking-the-leakage-effect-in-meeg-source","repo_url":"https://github.com/dpazlinares/BC-VARETA","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":1,"framework":"none","reach":null},{"paper_slug":"caulking-the-leakage-effect-in-meeg-source","repo_url":"https://github.com/CCC-members/BC-VARETA_Toolbox","is_official":0,"mentioned_in_paper":0,"mentioned_in_github":1,"framework":"none","reach":null},{"paper_slug":"caulking-the-leakage-effect-in-meeg-source","repo_url":"https://github.com/denysbuedo/BC-VARETA-toolbox-master","is_official":0,"mentioned_in_paper":0,"mentioned_in_github":1,"framework":"none","reach":null},{"paper_slug":"caulking-the-leakage-effect-in-meeg-source","repo_url":"https://github.com/denysbuedo/BC-Vareta2","is_official":0,"mentioned_in_paper":0,"mentioned_in_github":1,"framework":"none","reach":null},{"paper_slug":"caulking-the-leakage-effect-in-meeg-source","repo_url":"https://github.com/denysbuedo/BC_VaretaModel","is_official":0,"mentioned_in_paper":0,"mentioned_in_github":1,"framework":"none","reach":null},{"paper_slug":"caulking-the-leakage-effect-in-meeg-source","repo_url":"https://github.com/denysbuedo/Jenkins-pl_BC-Vareta_simple-subject","is_official":0,"mentioned_in_paper":0,"mentioned_in_github":1,"framework":"none","reach":null},{"paper_slug":"caulking-the-leakage-effect-in-meeg-source","repo_url":"https://github.com/dpazlinares/BC-VARETA-simpack","is_official":0,"mentioned_in_paper":0,"mentioned_in_github":1,"framework":"none","reach":null},{"paper_slug":"caulking-the-leakage-effect-in-meeg-source","repo_url":"https://github.com/egmoreira/BC-VARETA-toolbox","is_official":0,"mentioned_in_paper":0,"mentioned_in_github":1,"framework":"none","reach":null}],"tasks":[{"task_slug":"connectivity-estimation","task_name":"Connectivity Estimation"},{"task_slug":"time-series","task_name":"Time Series Analysis"}],"methods":[],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"syntology_url":null,"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}