{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/benchmarking-tools-for-a-priori","title":"Benchmarking tools for a priori identifiability analysis","arxiv_id":"2207.09745","date":"2022-07-20","proceeding":null,"authors":["Xabier Rey Barreiro","Alejandro F. Villaverde"],"abstract":"The structural identifiability and the observability of a model determine the possibility of inferring its parameters and states by observing its outputs. These properties should be analysed before attempting to calibrate a model. Unfortunately, such \\textit{a priori} analysis can be challenging, since it requires symbolic calculations that often have a high computational cost. In recent years a number of software tools have been developed for this task, mostly in the systems biology community but also in other disciplines. These tools have vastly different features and capabilities, and a critical assessment of their performance is still lacking. Here we present a comprehensive study of the computational resources available for analysing structural identifiability. We consider 12 software tools developed in 7 programming languages (Matlab, Maple, Mathematica, Julia, Python, Reduce, and Maxima), and evaluate their performance using a set of 25 case studies created from 21 models. Our results reveal their strengths and weaknesses, provide guidelines for choosing the most appropriate tool for a given problem, and highlight opportunities for future developments.","url_abs":"https://arxiv.org/abs/2207.09745v3","url_pdf":"https://arxiv.org/pdf/2207.09745v3.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"benchmarking-tools-for-a-priori","repo_url":"https://github.com/xabo-rb/benchmarking_files","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":1,"framework":"none","reach":null}],"tasks":[{"task_slug":"benchmarking","task_name":"Benchmarking"}],"methods":[],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}