{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/adaptation-of-olfactory-receptor-abundances","title":"Adaptation of olfactory receptor abundances for efficient coding","arxiv_id":"1801.09300","date":"2019-01-22","proceeding":null,"authors":[],"abstract":"Olfactory receptor usage is highly heterogeneous, with some receptor types\nbeing orders of magnitude more abundant than others. We propose an explanation\nfor this striking fact: the receptor distribution is tuned to maximally\nrepresent information about the olfactory environment in a regime of efficient\ncoding that is sensitive to the global context of correlated sensor responses.\nThis model predicts that in mammals, where olfactory sensory neurons are\nreplaced regularly, receptor abundances should continuously adapt to odor\nstatistics. Experimentally, increased exposure to odorants leads variously, but\nreproducibly, to increased, decreased, or unchanged abundances of different\nactivated receptors. We demonstrate that this diversity of effects is required\nfor efficient coding when sensors are broadly correlated, and provide an\nalgorithm for predicting which olfactory receptors should increase or decrease\nin abundance following specific environmental changes. Finally, we give simple\ndynamical rules for neural birth and death processes that might underlie this\nadaptation.","url_abs":"http://arxiv.org/abs/1801.09300v4","url_pdf":"http://arxiv.org/pdf/1801.09300v4.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"adaptation-of-olfactory-receptor-abundances","repo_url":"https://github.com/ttesileanu/OlfactoryReceptorDistribution","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":0,"framework":"none","reach":null}],"tasks":[{"task_slug":"diversity","task_name":"Diversity"}],"methods":[],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"syntology_url":null,"atlas_url":null,"mcp":null,"developers":"https://syntology.ai/developers"},"arxiv_metadata":null,"syntology_extracted_results":null}