{"about":{"site":"https://codewithpapers.app","non_affiliation":"Code with Papers and Syntology are not affiliated with, endorsed by, or sponsored by Papers with Code, Meta, or the pwc-archive mirror.","licence":"CC BY-SA 4.0","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","attribution":"https://codewithpapers.app/attribution","modified":"archive material modified by Syntology; see the attribution page"},"url":"/paper/a-refer-and-ground-multimodal-large-language","title":"A Refer-and-Ground Multimodal Large Language Model for Biomedicine","arxiv_id":"2406.18146","date":"2024-06-26","proceeding":null,"authors":["Xiaoshuang Huang","Haifeng Huang","Lingdong Shen","Yehui Yang","Fangxin Shang","Junwei Liu","Jia Liu"],"abstract":"With the rapid development of multimodal large language models (MLLMs), especially their capabilities in visual chat through refer and ground functionalities, their significance is increasingly recognized. However, the biomedical field currently exhibits a substantial gap in this area, primarily due to the absence of a dedicated refer and ground dataset for biomedical images. To address this challenge, we devised the Med-GRIT-270k dataset. It comprises 270k question-and-answer pairs and spans eight distinct medical imaging modalities. Most importantly, it is the first dedicated to the biomedical domain and integrating refer and ground conversations. The key idea is to sample large-scale biomedical image-mask pairs from medical segmentation datasets and generate instruction datasets from text using chatGPT. Additionally, we introduce a Refer-and-Ground Multimodal Large Language Model for Biomedicine (BiRD) by using this dataset and multi-task instruction learning. Extensive experiments have corroborated the efficacy of the Med-GRIT-270k dataset and the multi-modal, fine-grained interactive capabilities of the BiRD model. This holds significant reference value for the exploration and development of intelligent biomedical assistants.","url_abs":"https://arxiv.org/abs/2406.18146v2","url_pdf":"https://arxiv.org/pdf/2406.18146v2.pdf","source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28","licence_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","row_kind":"abstracts"},"code_links":[{"paper_slug":"a-refer-and-ground-multimodal-large-language","repo_url":"https://github.com/shawnhuang497/bird","is_official":1,"mentioned_in_paper":1,"mentioned_in_github":1,"framework":"paddle","reach":{"status":"ok","spdx":"Apache-2.0"}}],"tasks":[{"task_slug":"language-modeling","task_name":"Language Modeling"},{"task_slug":"language-modelling","task_name":"Language Modelling"},{"task_slug":"large-language-model","task_name":"Large Language Model"},{"task_slug":"multimodal-large-language-model","task_name":"Multimodal Large Language Model"}],"methods":[],"datasets_introduced":[],"methods_introduced":[],"results":[],"syntology":{"syntology_url":"https://syntology.ai/paper/2406.18146","atlas_url":"https://app.syntology.ai/?focus=2406.18146","mcp":{"get_harvested_code_for_paper":{"arxiv_id":"2406.18146"}},"developers":"https://syntology.ai/developers","read_at":"2026-09-25T09:33:49+00:00","read_at_is":"when the build read Syntology's graph, not when any sample ran","claim":"Per-sample execution status on synthesized fixtures; not a correctness claim about the paper. 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