{"url":"/dataset/cath-4-2","name":"CATH 4.2","full_name":null,"description_markdown":"The CATH (Class, Architecture, Topology, Homology) [65] database is a comprehensive\r\nresource for protein structure classification that hierarchical group proteins based on their structural\r\nfeatures. The database defines classes based on topological similarities, architectures based on the\r\narrangement of secondary structure elements, topologies based on the connectivity of secondary\r\nstructure elements, and homologous domains based on sequence similarity.","description_withheld":null,"homepage":"https://cathdb.info/wiki/doku/?id=index","introduced_date":null,"introduced_date_note":null,"introduced_by":null,"license":null,"modalities":[{"name":"Biology","url":"/datasets/modality/biology"}],"tasks":[{"name":"Protein Design","url":"/task/protein-design","datasets_with_task":"/datasets/task/protein-design"},{"name":"Protein Language Model","url":"/task/protein-language-model","datasets_with_task":"/datasets/task/protein-language-model"}],"languages":[],"variants":["CATH 4.2"],"data_loaders":[],"num_papers_in_archive":1,"source":{"archive":"pwc-archive (Hugging Face), CC BY-SA 4.0","snapshot":"2025-07-28"},"benchmarks":[{"leaderboard":"/sota/protein-design-on-cath-4-2","task":"Protein Design","dataset_variant":"CATH 4.2","rows":8,"metrics":["Perplexity","Sequence Recovery %(All)"],"first_row_in_archive_order":{"model":"Knowledge-Design","paper":"/paper/knowledge-design-pushing-the-limit-of-protein","metrics":{"Perplexity":"3.46","Sequence Recovery %(All)":"60.77"},"code_links":[{"title":"A4Bio/OpenCPD","url":"https://github.com/A4Bio/OpenCPD"}]},"note":"rows are the archive's own order at snapshot; nothing here re-ranks them"}],"papers_with_a_benchmark_row":[{"paper":"/paper/knowledge-design-pushing-the-limit-of-protein","title":"Knowledge-Design: Pushing the Limit of Protein Design via Knowledge Refinement","date":"2023-05-20","rows_on_this_dataset":8,"code_links":1,"syntology":null}],"syntology_totals":{"read_at":"2026-09-24T18:15:14+00:00","papers_with_samples":0,"samples_harvested":0,"samples_ran":0,"samples_unverified":0,"pointer_only_for_licence":0,"papers_with_no_sample_that_ran":0,"note":"the per-paper counts above, summed; not a rate"},"papers_note":"The archive never published its papers-using-dataset list; these are papers with a leaderboard row on this dataset's benchmarks."}